What is Perivillous fibrin deposition?
Massive perivillous fibrin deposition (MPFD, or MFD) refers to excessive deposition of fibrous tissue around the chorionic villi of the placenta. It causes reduced growth of the foetus, and leads to miscarriage in nearly 1 in 3 pregnancies affected.
What is Subchorionic fibrin deposition?
Subchorionic fibrin deposition is seen as a laminated white plaque that is usually roughly triangular, with the base of the triangle fused with the undersurface of the chorionic plate and the apex protruding into the placental substance (Figs 5.8 and 5.9).
What is maternal floor infarction?
Maternal floor infarction is a relatively rare condition characterized clinically by severe early onset fetal growth restriction with features of uteroplacental insufficiency. It has a very high recurrence rate and carries a significant risk or fetal demise.
What causes Subchorionic fibrin deposition?
Children who were hyperactive at one year of age had increased levels of subchorionic fibrin, which suggests that they were hyperactive before birth. All of these findings raise the possibility that normal fetal movements sometimes traumatize the placenta, which leads to fibrin deposits beneath its surface.
What is fibrin in the lungs?
Data summary: Alveolar fibrin deposition is characteristic of diverse forms of acute lung injury. Intravascular thrombosis or disseminated intravascular coagulation can also occur in the acutely injured lung. Extravascular fibrin deposition promotes lung dysfunction and the acute inflammatory response.
Why is it important to check every placenta?
Examination of the placenta can yield information that may be important in the immediate and later management of mother and infant. This information may also be essential for protecting the attending physician in the event of an adverse maternal or fetal outcome.
What is a placental infarction?
Placental infarction refers to a localized area of ischemic villous necrosis. It is a significant cause of placental insufficiency.
What causes placenta infarction?
Placental infarcts are areas of dead tissue found within the placenta, typically caused by blood vessel complications. This placental abnormality decreases blood flow to the affected areas. At times, this can cause fetal growth restriction or death.
What causes Chorangiosis?
Chorangiosis is a vascular change involving the terminal chorionic villi in the placenta. It results from longstanding, low-grade hypoxia in the placental tissue, and is associated with such conditions as intrauterine growth restriction (IUGR), diabetes, and gestational hypertension in pregnancy.
What is acute Subchorionitis?
Acute subchorionitis, chorioamnionitis, and funisitis are considered placental histologic features consistent with acute inflammation according to the Society for Pediatric Pathology.
What is acute funisitis?
(A) Typically, acute funisitis begins as inflammation of the umbilical vein (umbilical phlebitis; the red vessel represents the umbilical vein), followed by umbilical arteritis involving the umbilical arteries (blue). (B) Progression of inflammation along the length of the umbilical cord.