What do Sclerotomes do?
The sclerotome forms the vertebrae and the rib cartilage and part of the occipital bone; the myotome forms the musculature of the back, the ribs and the limbs; the syndetome forms the tendons and the dermatome forms the skin on the back.
What is the function of somites?
Somites give rise to the cells that form the vertebrae and ribs, the dermis of the dorsal skin, the skeletal muscles of the back, and the skeletal muscles of the body wall and limbs.
What is meant by sclerotome?
Medical Definition of sclerotome : the ventral and mesial portion of a somite that proliferates mesenchyme which migrates about the notochord to form the axial skeleton and ribs.
What are somites in anatomy?
Somites are precursor populations of cells that give rise to important structures associated with the vertebrate body plan and will eventually differentiate into dermis, skeletal muscle, cartilage, tendons, and vertebrae. Formation begins as paraxial mesoderm cells organize into whorls of cells called somitomeres.
How are Sclerotomes formed?
The avian sclerotome forms by epitheliomesenchymal transition of the ventral half-somite. Sclerotome development is characterized by a craniocaudal polarization, resegmentation, and axial identity. Its formation is controlled by signals from the notochord, the neural tube, the lateral plate mesoderm, and the myotome.
What does Epiblast become?
The epiblast gives rise to the three primary germ layers (ectoderm, definitive endoderm, and mesoderm) and to the extraembryonic mesoderm of the visceral yolk sac, the allantois, and the amnion.
What is a Myotome?
Myotome. The anatomical term myotome refers to the muscles served by a spinal nerve root. A myotome is, therefore, a set of muscles innervated by a specific, single spinal nerve. The term is also used in embryology to describe that part of the somite which develops into the muscles.
What does ectoderm mean?
The ectoderm is the outermost of the three layers. It differentiates to give rise to many important tissues and structures including the outer layer of the skin and its appendages (the sweat glands, hair, and nails), the teeth, the lens of the eye, parts of the inner ear, the nerves, brain, and spinal cord.
What are the functions of ectoderm and endoderm?
The ectoderm gives rise to the nervous system and the epidermal skin cells, the mesoderm gives rise to the muscle cells and connective tissue in the body, and the endoderm gives rise to the digestive system and other internal organs.
What is the dictionary definition of a sclerotome?
Zoology. a fibrous partition separating successive myotomes. The Dictionary added new words and definition to our vast collection, and we want to see how well-versed you are in the formally recognized new lingo. Take the quiz!
Is the sclerotome the origin of the axial skeleton?
The sclerotome. The sclerotome, which is the origin of the axial skeleton, is formed from the ventromedial part of the somite (reviewed in Monsoro-Burq, 2005 ). Sclerotomal induction entails an epithelial-to-mesenchymal transformation of the relevant somitic cells and their detachment from the epithelial somite.
How is the sclerotome organized during its development?
During development the sclerotome is organized into a patterned structure of alternating loose and dense mesenchyme. The dense mesenchyme will differentiate into the AF of the IVD, and the loose mesenchyme will differentiate into the VB. A sharp boundary exists between the two compartments due to the differential expression of certain factors.
What does sclero stand for in medical terms?
sclero·tome | \\ ˈskler-ə-ˌtōm \\. : the ventral and mesial portion of a somite that proliferates mesenchyme which migrates about the notochord to form the axial skeleton and ribs.