Which is the theory of mucoadhesion?
Mucoadhesion is currently explained by six theories: electronic, adsorption, wettability, diffusion, fracture and mechanical. Several in vitro and in vivo methodologies are proposed for studying its mechanisms. However, mucoadhesion is not yet well understood.
What is bioadhesive property?
From Wikipedia, the free encyclopedia. Bioadhesives are natural polymeric materials that act as adhesives. The term is sometimes used more loosely to describe a glue formed synthetically from biological monomers such as sugars, or to mean a synthetic material designed to adhere to biological tissue.
Is an example of bioadhesive polymer?
Classification of bioadhesive polymers. Matrices developed with these polymers swell when put into an aqueous media with subsequent dissolution of the matrix, for example, methyl cellulose, hydroxyethyl cellulose, hydroxypropyl methylcellulose (HPMC), sodium carboxymethyl cellulose, carbomers, chitosan, and plant gums.
What are the characteristics of mucoadhesive systems?
Other desired characteristics of a mucoadhesive dosage form include high drug loading capacity, controlled drug release (preferably unidirectional release), good mucoadhesive properties, smooth surface, tastelessness, and convenient application.
What is the possible mechanism behind the Mucoadhesion?
Mucoadhesion involves several types of bonding mechanisms, and it is the interaction between each process that allows for the adhesive process. The major categories are wetting theory, adsorption theory, diffusion theory, electrostatic theory, and fracture theory.
Which one of the following is an example of natural mucoadhesive?
Various natural polymers which can be used in mucoadhesive buccal films are chitosan, sodium alginate, tragacanth, gelatin and guar gum etc.
What is mucoadhesive drug delivery?
Mucoadhesive drug delivery systems are delivery systems which utilize the property of bioadhesion of certain polymers which become adhesive on hydration and hence can be used for targeting a drug to a particular region of the body for extended periods of time.