Which groups are present in sulfonamide?
In chemistry, the sulfonamide functional group (also spelled sulphonamide) is -S(=O)2-NH2, a sulfonyl group connected to an amine group. Relatively speaking this group is unreactive. The amine center is no longer basic.
Which amino group is present in Sulphanilamide?
This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
What is the structure of sulfonamides?
Structure of Sulfonamides Sulfonamides are composed of a sulfur atom that has two sets of double bonds to two oxygen atoms, a carbon-based side group, and a nitrogen atom bonded to the sulfur itself. In organic chemistry, an amide contains a carbonyl group bonded to a nitrogen atom.
Are sulfonamides basic or acidic?
The sulfonamide group, SO2NHR, is an acidic moiety that features heavily in pharmaceutical and agrochemical compounds, yet is surprisingly uncommon in nature.
Is sulfadiazine basic or acidic?
Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues.
Who should not take sulfonamides?
Who should not take?
- porphyria.
- anemia from inadequate folic acid.
- a blood disorder.
- liver problems.
- decreased kidney function.
- anemia from pyruvate kinase and G6PD deficiencies.
- third trimester of pregnancy.
What are examples of sulfonamides?
Examples of sulfonamides includes sulfadiazine, sulfamethizole (brand name: Thiosulfil Forte), sulfamethoxazole (Gantanol), sulfasalazine (Azulfidine), sulfisoxazole (Gantrisin), and various high-strength combinations of three sulfonamides. Sulfa drugs kill bacteria and fungi by interfering with cell metabolism.
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