How do you calculate hydromorphone?

How do you calculate hydromorphone?

Example: Change 90 mg q 12 Extended Release Morphine to oral Hydromorphone.

1. Calculate the 24 hour current dose: 90 Q12 x 2 = 180 mg PO Morphine/24 hrs.
2. Use the equianalgesic ratio: 30 mg PO Morphine = 7.5 mg PO Hydromorphone.
3. Calculate new dose using ratios: 180/30 X 7.5 = 45 mg oral Hydromorphone/24 hours.

Why is hydromorphone preferred over morphine?

Patients with bronchospasm: Fentanyl or hydromorphone is preferred over morphine as they cause the lesser release of histamine as compared to morphine.

What is cross tolerance of opioids?

It is the process of switching a patient who is highly tolerant to one opioid-selective drug to another to restore analgesia. It has been reported that analgesia may be restored by the second drug at doses 50% below the predicted equivalent dose determined by relative potency studies in naive subjects.

Is fentanyl a sedative or analgesic?

Fentanyl is a very potent synthetic opioid and one of the commonly used analgesic adjuncts in the ED. It rapidly crosses the blood-brain barrier and thus has a rapid onset of analgesia (< 90 s).

Which is better hydromorphone or Tramadol?

Tramadol is less effective in controlling visceral pain compared to hydromorphone. However, tramadol can help to alleviate anxiety and depression in the early postpartum period, improve patients’ early mobilization and shorten their hospital stay.

What are the equivalent doses of fentanyl and sufentanil?

The patients received equivalent doses of fentanyl 2 lag/kg, sufentanil 0.2 lag/kg, or remifentanil 2 lag/kg via IV push.

How much does it cost to get an anesthetic for remifentanil?

Median anesthetic costs were largest in the Remifentanil group ($140.54 113.54–$179.29]) and smallest in the Fentanyl group ($43.33 [$39.36–$56.48]) (P ≤ 0.01), but hospital costs were similar in the three groups: $7841 (Fentanyl), $5943 (Sufentanil), and $6286 (Remifentanil) (P > 0.05).

Can you take remifentanil at the same time as fentanyl?

All Remifentanil group patients received fentanyl 250 μg as part of the induction. We believed that this would decrease the remifentanil dose needed for the induction, provide some initial postoperative analgesia (when the remifentanil was discontinued), and have minimal effects on the rest of the postoperative course.

What’s the difference between remifentanil and alfentanil?

This study investigated the relative potency of remifentanil compared with alfentanil. Thirty young healthy males were administered double-blind remifentanil or alfentanil intravenously for 180 min using a computer-assisted continuous infusion device.