What is a VMA 24-hour urine test?
This test measures the amount of VMA that is passed into the urine, typically over a 24-hour period, to detect excess epinephrine and norepinephrine. It is used to detect tumors called neuroblastomas and other neuroendocrine tumors.
What is a urine VMA?
Vanillylmandelic acid (VMA) and other catecholamine metabolites such as homovanillic acid (HVA) measurement in urine are used for screening children for catecholamine-secreting tumors such as neuroblastoma and other neural crest tumors and monitoring those who have had treatment for these tumors.
What does elevated VMA mean?
Vanillylmandelic acid (VMA) and other catecholamine metabolites (homovanillic acid: HVA and dopamine) are typically elevated in patients with catecholamine-secreting tumors (eg, neuroblastoma, pheochromocytoma, and other neural crest tumors).
What test collects urine for 24 hours?
A 24-hour urine protein test measures the amount of albumin in your urine over 24 hours. Your kidneys filter protein from your body and then absorb it. When it’s sent back into your blood, waste products are removed from your body as urine.
What is metanephrines 24-hour urine test for?
Urine metanephrines testing is used to help detect or rule out the presence of a rare tumor called a pheochromocytoma or a paraganglioma that releases excess metanephrines. Since these tumors (PPGL) produce these hormones in excess, measuring the amount in the blood and/or urine may help detect the tumors.
Why do I need a 24-hour urine test?
A 24-hour urine collection helps diagnose kidney problems. It is often done to see how much creatinine clears through the kidneys. It’s also done to measure protein, hormones, minerals, and other chemical compounds.
What is normal VMA level?
Normetanephrine: 75 to 375 mcg/24 hours. Total urine catecholamines: 14 to 110 mcg/24 hours. VMA: 2 to 7 milligrams (mg)/24 hours (10 to 35 mcmol/24 hours)
What does high levels of Metanephrine in urine mean?
If your 24-hour metanephrine level is twice the normal level or higher, it’s likely that you have a pheochromocytoma or paraganglioma. You may need to have imaging tests, including CT or MRI scans. These tests are done to confirm the diagnosis and find the tumor.
Why would a doctor order a 24-hour urine test?
What are normal results for a 24-hour urine test?
The normal range for 24-hour urine volume is 800 to 2,000 milliliters per day (with a normal fluid intake of about 2 liters per day).
What causes high metanephrines in urine?
Certain medicines, foods, and conditions can cause metanephrine and catecholamine levels to be higher than normal. These include: Antidepressants and amphetamines. Physical or emotional stress.