What is Fibroblastic osteosarcoma?
Approximately 25% of osteosarcomas consist predominantly of spindle tumor cells and can be classified as fibroblastic osteosarcoma. Osteoid production is minimal and seen focally; although in this case, osteoid matrix was readily found. Fibroblastic osteosarcomas are highly vascular and may resemble hemangiopericytoma.
What type of radiation is used for osteosarcoma?
External beam radiation therapy. This is the type of radiation therapy most often used to treat osteosarcoma. A machine outside the body focuses high-energy beams on the tumor to kill the cancer cells.
What is the etiology of osteosarcoma?
Most osteosarcomas are not caused by inherited gene mutations, but instead are the result of gene changes acquired during the person’s lifetime. Sometimes these gene changes are caused by radiation therapy used to treat another form of cancer, because radiation can damage the DNA inside cells.
Does radiation treatment weaken bones?
Exposure to chemotherapy and radiation leads to bone loss and increases the risk of osteoporosis and fractures.
Does radiation destroy bone?
Bone weakness in the treated bone, which may break (fracture) more easily. Second cancers are more likely to form in areas that been treated with radiation. These cancers may develop even decades after treatment.
What are the odds of surviving osteosarcoma?
Survival rates can give you an idea of what percentage of people with the same type and stage of cancer are still alive a certain amount of time (usually 5 years) after they were diagnosed….Osteosarcoma 5-year relative survival rates.
SEER stage | 5-year relative survival rate |
---|---|
Distant | 27% |
All SEER stages combined | 60% |
Can osteosarcoma be malignant?
It happens when the cells that grow new bone form a cancerous tumor. Treatment — chemotherapy and surgery to take out the tumor — is usually successful when the disease is diagnosed early, before it can spread. Anyone can have osteosarcoma, but it’s the most common kind of bone cancer in children and teens.