What is in demineralized bone matrix?
Demineralized bone matrix (DBM) is an osteoconductive scaffold that is manufactured by acid extraction of allograft bone. While it provides no structural support, it contains noncollagenous proteins, osteoinductive growth factors, and type I collagen.
What is Grafton DBM?
WHAT IS GRAFTON DBM? GraftonTM Demineralized Bone Matrix (DBM) is an allograft tissue, which means it is from a human donor, and thoroughly tested and processed to ensure safety and sterility. Allograft bone is well documented in clinical studies and has an excellent safety record.
What is Grafton DBF?
Grafton™ DBF Inject is a precisely controlled bone graft delivery system that enables pre- and post-packing of graft material in the interbody space through integrated cannulas. It can be used with certain Medtronic interbody devices, when hydrated with bone marrow aspirate (BMA) for spinal and orthopedic procedures.
What is Grafton allograft?
Grafton is a human bone allograft product containing demineralized human bone tissue combined with inert additive to yield a demineralized bone matrix (DBM) allograft. The voids or gaps may be surgically created defects or effects created by traumatic injury to the bone.
Is bone demineralization the same as osteoporosis?
Bone demineralization is a precursor to osteopenia but not necessarily osteoporosis or osteoarthritis. Osteoporosis occurs when the creation of new bone doesn’t keep up with the loss of old bone. The results of a bone density scan will assist the provider in determining bone treatment options when needed.
How does demineralized bone matrix work?
Demineralized Bone Matrix (DBM) is a type of bone graft alternative that is processed from human allograft bone. DBM is processed by removing the mineral component of bone with acid, leaving behind the extracellular matrix composed of collagen and non-collagenous proteins, including the endogenous growth factors.
What is Orthoblend?
Available in two distinct formulations, Grafton™ Orthoblend combines demineralized bone fibers with cancellous chips or crushed cancellous chips.
Is DBM synthetic?
There are several main types of bone graft substitutes used in spinal fusion surgery, which can be generally categorized into three main areas: Demineralized Bone Matrix (DBM) Synthetic bone graft extenders. Bone Morphogenetic Proteins (BMP).
What is bioventus Osteoamp?
OSTEOAMP is a differentiated allograft, uniquely processed with the bone and the bone marrow to retain multiple growth factors. 1* OSTEOAMP formats include granules and putty. Explore our OSTEOAMP SELECT formats (flowable, fibers, sponges). See clinical data.
Can bone demineralization be reversed?
Your doctor diagnoses osteoporosis based on bone density loss. You can have different degrees of the condition, and catching it early can help you prevent the condition from worsening. You cannot reverse bone loss on your own.
Is bone demineralization painful?
Major signs and symptoms of bone demineralization in osteomalacia are achy bone pain and skeletal muscle weakness, fractures, and other complications (TABLE 1).