What is the therapeutic INR range for prosthetic heart valves?
In patients with mechanical heart valves in both the aortic and mitral position, a target INR of 3.0 (range 2.5 to 3.5) is suggested over a target INR of 2.5.
What are the target values for prosthetic valves receiving warfarin?
We conclude that after implantation of new generation prosthetic mechanical mitral valves, patients should receive warfarin to a target INR of 2.5-3.5. For older types of valve the target INR should be 3.5-4.5.
What is the optimal INR level?
Current guidelines recommend that patients on warfarin should have an international normalized ratio (INR) of 2-3, and that the time in therapeutic range (TTR) should be more than 70%;[3, 12] however, most patients with NVAF in many Asian countries have a TTR of less than 70% – even in controlled settings, such as …
What is the target INR?
In most situations the INR target is 2.5 (target range 2.0 – 3.0). This range is appropriate for the prophylaxis or treatment of venous thromboembolism and reduction of the risk of systemic embolism for people with atrial fibrillation and valvular heart disease.
What causes INR to fluctuate?
Foods with high levels of vitamin K include kale, broccoli, and Brussels sprouts. Other changes to your nutrition, such as starting a new diet or taking new supplements, can also cause your INR level to fluctuate. Talk to your doctor before starting any new diet/nutrition regimens.
What drug is given as an antidote to warfarin?
Vitamin K (phytonadione) Kcentra. FFP (fresh frozen plasma)
Why is mechanical valve INR higher?
Current American and European clinical guidelines recommend a higher international normalized ratio (INR) for anticoagulant therapy after mechanical mitral valve replacement, because higher rates of thromboembolic complications were reported when the mechanical valve was in the mitral position, as compared to when the …
Is 2.9 A high INR?
A typical INR target ranges from 2-3 but can vary from patient to patient. Patients with a tendency towards clotting may have a range targeting 3-4, whereas patients with a higher bleeding risk may have a lower INR between 2-2.5.
Can high INR cause stroke?
People not taking warfarin have an INR of around 1 but patients with a mechanical heart valve should have an INR in the range of 2.5 to 3.5 to prevent their body creating a blood clot which could travel to the brain and cause a stroke.
What can make your INR go up?
What increases my risk for an elevated INR?
- Too much anticoagulant medicine, a type of blood thinner that helps prevent clots.
- Other medicines, such as aspirin, NSAIDs, and some antibiotics, when you also are using anticoagulants.
- Health conditions, such as liver failure or bleeding disorders.
Why do you take warfarin at 6pm?
In order to shorten the response time for making a dosing change, patients are traditionally advised to have their INR test in the morning and to take their warfarin in the evening (so that the INR test result will be back in time to change that day’s warfarin dose if needed).
How do you keep your INR stable?
To keep your INR stable and within the recommended range it is important to: Eat the same number of servings of high Vitamin K foods each week. A good rule is, the greener the plant the higher the Vitamin K level.
Is Saint Jude a mechanical heart valve?
St. Jude Mitral Mechanical Valve is an example of a mechanical heart valve. Mechanical heart valves have an advantage over tissue valves in that they last a lifetime. More than 90% of all mechanical valves in the United States are St. Jude valves.
What is Saint Jude heart valve?
The St. Jude Medical cardiac valve is a low-profile, bileaflet, central-flow prosthesis made entirely of pyrolytic carbon.
What is Saint Jude valve?
St. Jude Medical was founded in 1976 to further develop bi-leaflet artificial heart valves, which were originally created in 1972 at the University of Minnesota. St. Jude Medical’s bi-leaflet valve was developed in large part by Dr. Demetre Nicoloff of the University of Minnesota and St. Jude Medical employee Don Hanson.