What is Tulathromycin used for?
Tulathromycin, sold under the brand name Draxxin among others, is a macrolide antibiotic used to treat bovine respiratory disease (BRD) in cattle and swine respiratory disease in pigs. It is supplied as a solution for injection containing 100 mg of the drug.
Can Draxxin be used in horses?
Horses were administered tulathromycin (Draxxin® 100 mg/ml; Zoetis US, Parsippany, NJ, USA) as a single dose of 2.5 mg/kg. For the IM and SC dosing, tulathromycin administration was performed in one site at the caudal aspect of the neck, without redirection of the needle, on the side opposite IV catheter placement.
What is generic for Draxxin?
Macrosyn and Increxxa contain the same active ingredient (tulathromycin) in the same concentration and dosage form as the approved brand name drug product, Draxxin, which was first approved in 2005.
What is Micotil?
Description. Micotil is a solution of the antibiotic tilmicosin. Each mL contains 300 mg of tilmicosin, USP as tilmicosin phosphate in 25% propylene glycol, phosphoric acid as needed to adjust pH and water for injection, Q.S. Tilmicosin, USP is produced semi-synthetically and is in the macrolide class of antibiotics.
Is Draxxin harmful to humans?
Draxxin can cause eye irritation. If Draxxin accidentally gets into the eyes, they should be flushed immediately with clean water. Draxxin may also cause sensitisation (redness, itching and swelling) if it comes into contact with the skin.
Where do you inject Draxxin?
Inject subcutaneously as a single dose in the neck at a dosage of 2.5 mg/kg (1.1 mL/100 lb) body weight (BW). Do not inject more than 10 mL per injection site.
Can you give a dog Draxxin?
Nuflor and Draxxin are only suggested if ferals and/or difficult to medicate animals are more than occasional clients. With my own experience as a guide, client compliance is King. Thus SID medications are preferred over BID, and TID/QID medications are reserved for the cash-strapped AND motivated clients.
How much DRAXXIN do you give a goat?
Recommended dosages for Draxxin ® in goats are as follows (Adapted from Plumb’s Veterinary Drugs, extra-label): 2.5 mg/kg SC; repeat in 7 days if necessary. Based on pharmacokinetic studies in meat and dairy goats, and FDA guidelines: a 34-day meat withdrawal interval and a 45 day milk withdrawal time are recommended.
Can you give DRAXXIN to pregnant cows?
Cattle. The effects of DRAXXIN on bovine reproductive performance, pregnancy, and lactation have not been determined. Subcutaneous injection can cause a transient local tissue reaction that may result in trim loss of edible tissue at slaughter.
Is there an antidote for Micotil?
There is no antidote to counteract the effects of Micotil. If an injection occurs, apply ice to the injection site and seek immediate medical attention.
What does Micotil do to humans?
Micotil is toxic to the heart and cardiovascular system, causing increased heart rate and changes in heart tissue. Human fatalities have been reported following injected doses as low as 3 to 5 cc.
How quickly does Draxxin work?
Cattle. Following subcutaneous administration into the neck of feeder calves at a dosage of 2.5 mg/kg BW, tulathromycin is rapidly and nearly completely absorbed. Peak plasma concentrations generally occur within 15 minutes after dosing and product relative bioavailability exceeds 90%.
How are tilmicosin phosphate and gamithromycin used in swine?
Tilmicosin, gamithromycin, and tulathromycin are approved for use in treatment of bovine respiratory diseases associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni. In swine, tilmicosin phosphate is added to feed or water for control of swine respiratory disease.
How does gamithromycin work as an antibiotic?
Gamithromycin is an antibacterial agent of the macrolide class of drugs. It is a 15-membered ring (like azithromycin and tulathromycin) macrolide. Like other macrolides, it inhibits bacterial protein synthesis by binding to the ribosomal 50S subunit.
How are azithromycin and Tulathromycin related?
Antibacterial related to the macrolide class of drugs. It is a 15-membered ring (like azithromycin and tulathromycin). Like other macrolides, it inhibits bacterial protein synthesis by binding to the ribosomal 50S subunit. It is considered bacteriostatic, but it may have bactericidal properties in vitro.
What kind of disease can Tulathromycin cause in pigs?
Tulathromycin has a spectrum of activity that is limited to gram-positive bacteria and some gram-negative bacteria that cause respiratory diseases in cattle and pigs (e.g., M. haemolytica, Mycoplasma spp., and P. multocida).