How long does Zofran IV last?
Zofran (ondansetron) lasts about eight hours. It begins to work quickly and reaches peak concentration in about two hours. To prevent nausea, the dose is usually repeated eight hours after the first one.
Can you get Zofran through IV?
Emetogenic chemotherapy and radiotherapy: Zofran can be given either by rectal, oral (tablets or syrup), intravenous or intramuscular administration.
Are side effects common with Zofran?
Common side effects associated with Zofran include headache, drowsiness, constipation and the chills. In clinical trials of patients taking Zofran to prevent nausea and vomiting associated with chemotherapy, nearly a quarter of patients taking 8 mg of the drug twice daily experienced a headache.
What is IV ondansetron?
Ondansetron injection is used to prevent nausea and vomiting caused by cancer chemotherapy and surgery. Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.
How quickly does Zofran start working?
How quickly does Zofran (ondansetron) work? Zofran (ondansetron) should work pretty quickly. Many people report relief within about 30 minutes and it reaches maximum blood concentrations in about 2 hours. The effects of Zofran (ondansetron) can last anywhere between 8 to 12 hours.
What happens if you push IV Zofran too fast?
Do not give this medication any faster than recommended or take more than the recommended dose because this may increase the chance of serious side effects such as blurred vision or slowed/irregular heartbeat.
How often can IV ondansetron be given?
Ondansetron should be administered immediately before chemotherapy as a single intravenous dose of 0.15 mg/kg. The intravenous dose must not exceed 8 mg. Two further intravenous doses may be given in 4-hourly intervals. The total daily dose must not exceed adult dose of 32 mg.
Why does Zofran cause constipation?
Zofran may cause headache, drowsiness, diarrhea, and constipation. It has been associated with QT prolongation and arrhythmias in those with heart conditions, electrolyte imbalances, and those taking other medications that prolong QT timing.
Does Zofran cause hypotension?
Summary: Hypotension is found among people who take Zofran, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Lasix , and have Pain. This study is created by eHealthMe based on reports of 57,921 people who have side effects when taking Zofran from Food and Drug Administration (FDA),…
How long can you take Zofran?
To protect against delayed or prolonged emesis after the first 24 hours, oral or rectal treatment with Zofran may be continued for up to 5 days after a course of treatment. The recommended dose for oral administration is 8 mg to be taken twice daily.
Can Zofran cause bradycardia?
Irregular heartbeats may develop in patients taking Zofran. According to the drug’s label, reported arrhythmias have included heartbeats that are too fast (tachycardia) or too slow (bradycardia) or that are too fast and originate from the wrong part of the heart (ventricular and supraventricular tachycardia).