What is considered a high ALP level?
Values above 130 U/L are usually considered to be high. High levels of ALP in the blood may indicate bone, liver, or bile duct disease. ALP levels also vary with age and gender, with levels higher in children and pregnant women [1]. Higher ALP levels can occur in people with blood group B or blood group O [2].
What causes alk phos to be elevated?
The most common causes of high ALP levels include: liver conditions, often bile duct obstructions. gallbladder conditions, usually gallstones. bone conditions, such as abnormal growths and occasionally cancers.
Can low vitamin D cause high alk phos?
Thus, vitamin D deficiency is usually accompanied by normal blood levels for calcium and phosphorus, high-normal or elevated levels of PTH, normal to elevated levels of total alkaline phosphatase, a low 24-hour urine calcium excretion rate, and low levels of total 25(OH)D.
Can vitamin D increase alkaline phosphatase?
The correlation coefficient of alkaline phosphatase and serum vitamin D3 levels was r =0.05 (p =0.593). Conclusion: Serum vitamin D3 levels may not be correlated with increased serum alkaline phosphatase levels. Therefore, alkaline phosphatase may not be used as a screening test to rule out vitamin D deficiency.
What causes a low alk phos?
Various causes may attribute to low ALP activity such as hypophosphatasia, cardiac surgery and cardiopulmonary bypass, blood collected with EDTA or oxalate anticoagulant, hypothyroidism, vitamin C and B12 deficiency, Milk alkali syndrome, protein/ calorie malnutrition, zinc and magnesium deficiency.
What causes high Alk Phos?
High alk. Phos can be caused by any/many liver disorders from any cause including hepatitis, obstruction of the bile due to stone or tumor.
What does it mean high Alk Phos?
High alkaline phosphatase levels may mean there is damage to your liver or that you have a type of bone disorder. Liver damage creates a different type of ALP than bone disorders do. If the test results show high alkaline phosphatase levels, your health care provider may order additional tests to find out where the extra ALP is coming from.
What does elevated Alk Phos mean?
Elevated Alkaline Phosphatase does not always mean you have problems with your liver. Sometimes Alkaline Phosphatase is elevated due to something simple, like eating a fatty meal that day. It can be elevated in children, during pregnancy due to increased metabolism, or in postmenopausal women due to a change in bone metabolism.
What medications can make alkaline phosphatase high?
Many common over-the-counter and prescription drugs can elevate alkaline phosphatase levels. For example, hypertension drugs such as propanolol or verapamil or gout treatments such as allopurinol can raise levels.